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49ers face injury crisis ahead of Saints showdown! Kittle out, Purdy questionable, and a new kicker in town – is an upset brewing in the Superdome? Can Jauan Jennings step up with Kittle sidelined? Will the Niners' dominant run defense stifle Alvin Kamara? Get the inside scoop on how these key factors could turn this game into a low-scoring defensive battle, decided by the finest of margins.

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