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Short Summary: A deep dive into the enigmatic world of sleep, exploring its biological functions, evolutionary origins, and the diverse manifestations across different species.
Note: Podcast episodes are fully available to paid subscribers on the M&M Substack and on YouTube. Partial versions are available elsewhere.
About the Guest: Vlad Vyazovskiy, PhD is a Professor of Sleep Physiology at the Department of Physiology, Anatomy, and Genetics at Oxford University.
Key Takeaways:
- Sleep as a Mystery: Despite extensive research, the fundamental reason why animals sleep remains elusive, with no comprehensive theory yet agreed upon.
- Local Sleep Phenomenon: Sleep might not be a whole-brain event; even within a sleeping brain, different areas can be in different states of activity or rest.
- Sleep in Animals: Sleep varies widely among species, from micro-sleeps in penguins to unihemispheric sleep in dolphins, suggesting sleep could serve multiple, context-dependent functions.
- Synaptic Homeostasis: The hypothesis suggests that sleep could be crucial for renormalizing synaptic connections formed during wakefulness, although this idea is still under scrutiny.
- Hibernation & Torpor: These states relate to sleep but involve significant metabolic changes, possibly acting as survival mechanisms by conserving energy and reducing detectability by predators.
- Psychedelics & Sleep: Research shows psychedelics like 5-MeO-DMT can induce states where animals show signs of sleep in their brain activity while physically active, hinting at complex interactions between brain states and consciousness.
Related episodes:
- M&M #43: Sleep, Dreaming, Deep Neural Networks, Machine Learning & Artificial Intelligence, Overfitted Brain Hypothesis, Evolution of Fiction & Art | Erik Hoel
- M&M #16: Sleep, Dreams, Memory & the Brain | Bob Stickgold
*Not medical advice.
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