#011-Glycans are being hailed as possibly the next great biological longevity clock. Today we speak with the leading expert on the subject.
Gordan Lauc PhD, is Professor of Biochemistry and Molecular biology at the University of Zagreb and Co-Founder and Chief Scientific Officer at GlycanAge. He graduated from the University of Zagreb Faculty of Science in 1992, and obtained PhD in Biochemistry and the University of Zagreb.
Take home points:
Glycans– the third revolution in evolution
Nuclei acids - 4 building blocks [linear]
Proteins - 20 amino acids [linear]
Glycoproteins- 2000+ [nonlinear]
Examples -Blood groups ABO are glycans
Post translational-make protein
Glycans modifications of proteins lipids and even DNA by sugar
Nonlinear branching oligosaccharide
Glucose-monosaccharide-
Post translational modifications-
Phosphorylation
Glycosylation
AGE- advanced glycation end products——reaction glucose and proteins- not the same as glycosylation.
Immunoglobulins- older get more pro inflammatory glycans-
Igg glycosylation suppress inflammation
Human glycan project
Health Longevity Secrets show listeners who wish to try The Glyconage longevity clock on themselves can receive a 20% discount enter the code ROBERTLUFKIN at theglycanage.com website.
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