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What are some factors involved in the development of Alzheimer's Disease? ApoE4 increases the risk of AD but how? What is the difference between brain ApoE and peripheral ApoE? What's the connection with microglia?

Check out episode 34 of vlmd rounds

Links:

The Magical Mystery Macrophage Tour: https://youtu.be/-CQqfkrae00

Lipoproteins episode: https://youtu.be/o9GU5ECGzs0