For two thousand years, this question has stumped commentators and inspired a lot of creative interpretations. There’s a consensus that Paul’s “thorn” in 2 Corinthians 12 is symbolic. Paul’s not referring to a literal thorn.
But what does the thorn represent?
Ryan's book on Paul, "The Weird Apostle": https://a.co/d/fsGrhg6
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Download the free PDF "Recovering the Jewish Paul: Three Keys to Understanding the Apostle and Building Bridges Between Jews and Christians"
The Weird Apostle
Ryan's book places the Apostle Paul in his Jewish and Greco-Roman context.