View all show notes and timestamps on the KoopCast website.
Episode overview:
Chiel Poffe is a Postdoctoral researcher at KU Leven. His areas of focus are energy metabolism and ketones.
Episode highlights:
(32:56) Practical ketone use: best during high-intensity training, 25g after exercise and before sleep, individual variance, potential improved sleep, muscle recovery, cognitive benefits, cost
(39:38) Ultramarathon study results: complications with investigating performance, reaction time test, no cognitive decline in ketone groups, ketone increase dopamine levels, mechanistic speculation
(45:19) Ketones aid cognition in extreme circumstances: revisiting study design, parallels to the overtraining study, ketones inhibit cognitive decline rather than improving cognition, support from initial ketone research
Additional resources:
Chiel on Twitter
Ketone ester supplementation blunts overreaching symptoms during endurance training overload
Exogenous ketosis increases circulating dopamine concentration and maintains mental alertness in ultra-endurance exercise
Outside Online’s dumb headline that ketones cure overtraining
Research Essentials for Ultrarunning: https://www.jasonkoop.com/research-essentials-for-ultrarunning
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