SUMMARY: At the 17th Monthly SubSaharan International Neurosurgery Grand Rounds meeting, the subject of the Management of Giant Brain tumors was discussed. These tumors are seen all over the world, usually related to people seeking medical care late in the disease. Dr. Eric Nussbaum, who has treated a number of these patents from outside the USA describes his experience with a patient who had a Giant Osteogenic Sarcoma and a second with an ossifying fibroma and Fibrous Dysplasia. Fibrous Dysphasia is a rare bone condition that happens when abnormal fibrous (scar-like) tissue replaces healthy bone tissue. It is not hereditary but is related to a GNAS1 gene changes after conception. This genetic change affects the osteoblasts. Major deformities occur as a result of this disease. See how Eric managed these diseases. What would you do? The widely known and respected African Professor Nim Juniahs Mwang'ombe of Kenya, makes some excellent comments on his experience with these tumors. Excellent for video and OK for Podcast, but the images must be seen to be appreciated. With the rise in Medical Tourism, patients with these types of lesions are treated locally and in countries in the developing world for less cost than in the USA. (A message for the developed countries as a trend for the future) (70 minutes presentation and discussion) First rate. (JIA)