At GI ReConnect in Denver, Dr. Carlo Di Lorenzo, pediatric gastroenterologist at Nationwide Children’s Hospital, moderates an in-depth conversation with Dr. Ankur Chugh of Children’s Wisconsin and Dr. Khalil El-Chammas of Cincinnati Children’s, exploring the evolving landscape of Congenital Sucrase-Isomaltase Deficiency (CSID). Together, these experts discuss how CSID is increasingly recognized as a potential mimicker of IBS and other GI disorders, and how their own clinical experiences have shaped their understanding of when to test, how to interpret pan-disaccharidase deficiencies, and what treatment strategies—such as enzyme therapy and dietary exclusion—may be most effective. The conversation highlights diagnostic challenges, the importance of biopsy technique and sample size, and the need for more consistent, longitudinal research to guide clinical decision-making. Whether you’re a pediatric or adult GI specialist, this discussion provides actionable insights and expert perspectives on a condition that’s more prevalent than previously thought. Presented by the GI Health Foundation, this episode underscores the need for collaboration and education to improve outcomes in patients with chronic abdominal pain and suspected carbohydrate malabsorption.
