Pain management requires a multimodal, patient-centered approach. In this episode, Amanda Latimore, PhD, and guests Jarratt Pytell, MD, and Arianna Campbell, MPH, PA-C, discuss comprehensive pain management strategies. Topics include opioid and non-opioid medications, short-acting opioids for acute pain, and nonpharmacologic therapies—with an emphasis on aligning treatment with patient goals; and the importance of communication, trust, and respect in patient care. By tuning in, listeners will gain essential insights into effective and safe pain management.