What does it mean to be emotionally blunted in terms of a patient's everyday life? Many patients treated with SSRIs or SNRIs report feeling emotionally detached, insensitive, or unable to have pleasure. This condition led to further research known as the Complete Study. The study provided key information on the efficacy of vortioxetine to treat emotional blunting. In this episode of Brilliant Together, Professor Andrea Fagiolini joins Global Senior Medical Advisor, Michael Cronquist Christensen, to share his view on the clinical objectives of the Complete Study, what results of the study he finds most remarkable, and the clinical implications of these findings for clinical practice.
Andrea Fagiolini is a Professor of Psychiatry at the University of Siena School of Medicine, Siena, Italy. He currently serves as Chairman, Chief of Medical Services, and Residency Training Director of the Department of Mental Health and Division of Psychiatry. He has published over 400 papers and book chapters in psychiatry and sits on the editorial boards of several international peer-reviewed journals in this field.
Key Takeaways:
[2:11] Professor Fagiolini shares his views on why it was important to do a study on emotional, and why Emotional Blunting is clinically critical to be addressed for patients with depression.
[6:47] Why Professor Fagiolini has a strong belief in studying the benefit of vortioxetine in treating emotionally blunted patients and how vortioxetine is different from other antidepressants based on his clinical experience.
[9:40] How the Complete Study was conducted and what the objective of the Complete Study is?
[14:55] Key findings of the Complete Study.
[23:12] Professor Fagiolini describes what makes the results of the Complete Study unique.
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