Our FAVORITE Magnesium is available HERE!
Shopping for magnesium can feel overwhelming with so many different forms on the shelf. From glycinate and citrate to oxide and L-threonate, every option claims its own distinct health benefits. In this episode, Pharmacist and Clinical Nutritionist Joey DiMatteo cuts through the marketing hype to explain the legitimate formulation science behind each type.
Whether you want to support nighttime relaxation, improve digestive regularity, boost cognitive performance, or support cardiovascular health, matching the right form to your specific health goals is essential. Joey breaks down the clinical evidence, practical dosing considerations, key drug interactions, and label reading tips to help you navigate the supplement aisle like a clinician.
IN THIS EPISODE, YOU'LL LEARN:
• Who should be supplementing magnesium.
• How each binding partner alters the benefit and cost of magnesium.
• Which forms of magnesium are best for overall daily supplementation.
• Why magnesium L-threonate, more than other forms, supports memory, focus, and brain health.
• The evidence behind high-dose magnesium protocols for prevention of migraines (with aura).
• How to read the Supplement Facts panel to calculate your actual dose of elemental magnesium.
• Key safety considerations, upper intake limits, and potential drug interactions to discuss with your doctor or pharmacist.
We love questions. Comment below or email us: questions@askjoedimatteo.com
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Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!
CHAPTERS:
00:00 - Show Intro
00:56 - Magnesium Basics
01:19 - What are Binding Partners?
02:50 - Who needs to supplement?
04:01 - Magnesium Glycinate
05:38 - Magnesium Citrate
07:16 - Magnesium Oxide
08:31 - Magnesium L-Threonate
09:50 - Magnesium Malate
10:50 - Magnesium Taurate
11:57 - Simpler Magnesium Forms
12:24 - Magnesium Sulfate
13:10 - Magnesium for Muscle Cramps
13:54 - Magnesium for Migraines
15:04 - Timing
15:56 - How to Read the Label
17:48 - How much magnesium should you take?
19:09 - Summary & Takeaway
SHOW NOTES:
1) US Magnesium Deficiencies (Study) - https://pmc.ncbi.nlm.nih.gov/articles/PMC6163803/
2) Mag Bisglycinate for Sleep (Study) - https://pubmed.ncbi.nlm.nih.gov/40918053/
3) Mag L-Threonate Cognition & Reaction Time (Study) - https://doi.org/10.3389/fnut.2025.1729164
4) Mag L-Threonate & Adults with Sleep Problems (Study) - https://doi.org/10.1016/j.sleepx.2024.100121
5) Mag L-Threonate & Cognitive Impaired Older Adults (Study) - https://pubmed.ncbi.nlm.nih.gov/26519439/
6) American Migraine Foundation (Article) - https://americanmigrainefoundation.org/resource-library/magnesium/
7) Magnesium & Migraines (Study) - https://pubmed.ncbi.nlm.nih.gov/26752497/
DISCLAIMER:
This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
