PCOS (Polycystic Ovary Syndrome) has, for millions of women, been the catch-all explanation for a host of symptoms like irregular periods, weight gain, acne, facial hair growth, and painful ovarian cysts. While our understanding has grown, the name often served as a distraction, and kept women from understanding the underlying cause. This led to people treating the immediate symptom without correcting the core problem. When The Lancet formally renamed PCOS to Polyendocrine Metabolic Ovarian Syndrome (PMOS), it signaled a massive shift in how clinicians are educating patients: this disease is simply too big for its old name.
Joey DiMatteo (PharmD, CCN) breaks down why this rebrand matters far beyond medical terminology. By reframing the condition around metabolic and hormonal complexity, this update shifts the focus from quick symptom management to root-cause treatment. The goal is long-term health rather than just fixing what's broken today. Don't get stuck in the PMOS spiral - Treat it at the source.
IN THIS EPISODE, YOU'LL LEARN:
• Why is PCOS being renamed to PMOS?
• Why erratic periods, weight gain, and acne can all signal one problem.
• How to stop the driver of PMOS
• Why a birth control prescriptions often misses the full diagnostic picture.
• Why follow-through on secondary bloodwork like A1c is vital for systemic health.
We love questions. Comment below or email us: questions@askjoedimatteo.com
CONNECT:
Products - https://askjoedimatteo.com/youtube
Questions - questions@askjoedimatteo.com
Facebook - https://facebook.com/askjoedimatteo
Instagram - https://tinyurl.com/5n6kfwhs
PODCAST:
Apple Podcasts - https://tinyurl.com/GHShowApple
Google Podcasts - https://tinyurl.com/GHShowYTM
Spotify - https://open.spotify.com/show/3B2v7PmHxLuxFoWOIWko8X?si=7ae14c5e6d1e449a
Rumble - https://rumble.com/user/GenerationHealth
YouTube Podcast - https://www.youtube.com/@GenerationHealthShow
YouTube Clips - https://www.youtube.com/@askjoedimatteo
Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!
CHAPTERS:
00:00 - Show Intro
00:21 - Lancet: PCOS is now PMOS
00:53 - Why is the name changing?
03:24 - What PMOS really means
05:41 - The metabolic health is the core.
10:04 - Complex Hormone Interplay in PMOS
12:26 - Is there a cure for PMOS?
15:03 - Insulin Resistance
16:48 - How medications factor in
17:52 - Takeaway: Control the Source
21:00 - Show Outro
SHOW NOTES:
1) PMOS - The New Name for PCOS (Lancet): https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)00717-8/fulltext
DISCLAIMER:
This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.
