In this episode, Dr. Caitlin Prickett and Jeffery Runyon explore the rising issue of polypharmacy in aging adults—when five or more medications are prescribed concurrently. They discuss the clinical risks, how to recognize medication overload, and the art and science of deprescribing. Backed by recent research, real-life stories, and practical tools, this episode empowers listeners to rethink their medication regimens and partner with their doctors to simplify care.