Hi, This Week in Medicine, we will be discussing
New England Journal of Medicine
Overall Survival with Pembrolizumab in Early-Stage Triple-Negative Breast Cancer
Fractional Doses of Pneumococcal Conjugate Vaccine — A Noninferiority Trial
Nivolumab plus Ipilimumab in Microsatellite-Instability–High Metastatic Colorectal Cancer
Journal of American Medical Association
Association of Severe Maternal Morbidity With Subsequent Birth
Intravenous Lidocaine for Gut Function Recovery in Colonic Surgery
Transcatheter Edge-to-Edge Repair for Severe Isolated Tricuspid Regurgitation
The Tri.Fr Randomized Clinical Trial
Annals of Internal Medicine
Association of Work Control With Burnout and Career Intentions Among U.S. Physicians: A Multi-Institution Stud
British Medical Journal
Contemporary menopausal hormone therapy and risk of cardiovascular disease
Lancet
Balloon guide catheters for endovascular thrombectomy in patients with acute ischaemic stroke due to large-vessel occlusion in China (PROTECT-MT): a multicentre, open-label, blinded-endpoint, randomised controlled trial
Cancer Journal for Clinicians
A phase 2 study of a brachyury-targeting vaccine in combination with radiation therapy for the treatment of advanced chordoma
Journal of Clinical Oncology
Prospective Study of Supplemental Screening With Contrast-Enhanced Mammography in Women With Elevated Risk of Breast Cancer: Results of the Prevalence Round
journal of Hepatology
Efficacy, tolerability and pharmacokinetics of survodutide, a glucagon/glucagon-like peptide-1 receptor dual agonist, in cirrhosis
Glutaryl-CoA dehydrogenase suppresses tumor progression and shapes an anti-tumor microenvironment in hepatocellular carcinoma
Gastroenterology
Gut Pathobiont–Derived Outer Membrane Vesicles Drive Liver Inflammation and Fibrosis in Primary Sclerosing Cholangitis–Associated Inflammatory Bowel Disease
Clinical Gastroenterology
Updated Reference Intervals for Alanine Aminotransferase in a Metabolically and Histologically Normal Population
Clinical Infectious Diseases
The Use of Long-term Antibiotics for Suppression of Bacterial Infections
Rheumatology
Implementing Patient Health Questionnaire Depression Screening in Inflammatory Arthritis Clinic
Journal of Clinical Rheumatology
Circulation
ErbB3 Governs Endothelial Dysfunction in Hypoxia-Induced Pulmonary Hypertension
Journals of the American College of Cardiology
Recaticimab Monotherapy for Nonfamilial Hypercholesterolemia and Mixed Hyperlipemia: The Phase 3 REMAIN-1 Randomized Trial
JAMA Cardiology
Routine Protamine Administration for Bleeding in Transcatheter Aortic Valve ImplantationThe ACE-PROTAVI Randomized Clinical Trial
Journal of Clinical Endocrinology & Metabolism
Obesity, Inflammation, and Clinical Outcomes in COVID-19: A Multicenter Prospective Cohort Study
Diabetes care
Choline Metabolites and 15-Year Risk of Incident Diabetes in a Prospective Cohort of Adults: Coronary Artery Risk Development in Young Adults (CARDIA) Study
Neurology
SGLT2 Inhibitor Use and Risk of Dementia and Parkinson Disease Among Patients With Type 2 Diabetes
Chest
Rethinking Blood Eosinophils for Assessing Inhaled Corticosteroids Response in COPD
The American Journal of Respiratory and Critical Care Medicine
Preacinar Arterial Dilation Mediates Outcomes of Quantitative Interstitial Abnormalities in the COPDGene Study
Clinical Journal of American Society of Nephrology
Acute Myocardial Infarction and Chronic Kidney Disease: A Nationwide Cohort Study on Management and Outcomes from 2010 to 2022
Kidney International reports
Randomized Trial of Patiromer on Efficacy to Reduce Episodic Hyperkalemia in Patients with ESKD Treated With Hemodialysis
