Hi, This Week in Medicine, we will be discussing
New England Journal of Medicine
Perioperative Chemotherapy or Preoperative Chemoradiotherapy in Esophageal Cancer
A Randomized Trial of Drug Route in Out-of-Hospital Cardiac Arrest
Intraosseous or Intravenous Vascular Access for Out-of-Hospital Cardiac Arrest
Abelacimab versus Rivaroxaban in Patients with Atrial Fibrillation
Journal of American Medical Association
Transanal vs Laparoscopic Total Mesorectal Excision and 3-Year Disease-Free Survival in Rectal Cancer: The TaLaR Randomized Clinical Trial
Question Is transanal total mesorectal excision (TME) noninferior to laparoscopic Annals of Internal Medicine
Census Tract Rurality, Predominant Race and Ethnicity, and Distance to Lung Cancer Screening Facilities
Assessing the Risk for Falls in Older Adults After Initiating Gabapentin Versus Duloxetine
British Medical Journal
Dapagliflozin plus calorie restriction for remission of type 2 diabetes
Lancet
Transarterial chemoembolisation combined with lenvatinib plus pembrolizumab versus dual placebo for unresectable, non-metastatic hepatocellular carcinoma (LEAP-012): a multicentre, randomised, double-blind, phase 3 study
Journal of Clinical Oncology
Efficacy and Safety of Roxadustat for Anemia in Patients Receiving Chemotherapy for Nonmyeloid Malignancies: A Randomized, Open-Label, Active-Controlled Phase III Study
journal of Hepatology
Induction of steatosis in primary human hepatocytes recapitulates key pathophysiological aspects of metabolic dysfunction-associated steatotic liver disease
Functional cure of hepatitis B in patients with cancer undergoing immune checkpoint inhibitor therapy
Gastroenterology
Glutamine Supplementation as a Novel Metabolic Therapeutic Strategy for LIG3-Dependent Chronic Intestinal Pseudo-Obstruction
Clinical Gastroenterology
Endoscopic Submucosal Dissection Criteria for Differentiated-type Early Gastric Cancer Are Applicable to Mixed-type Differentiated Predominant
Association Between Different Types of Physical Activity and Hepatic Steatosis and Liver Fibrosis: A Cross-Sectional Study Based on NHANES
Journal of Clinical Rheumatology
Preliminary Evaluation for the Development of a Scoring System to Predict Homozygous M694V Genotype in Familial Mediterranean Fever Patients: A Single-Center Study
Circulation
A Rare Noncoding Enhancer Variant in SCN5A Contributes to the High Prevalence of Brugada Syndrome in Thailand
Journals of the American College of Cardiology
Optimal Strategy for Complete Revascularization in ST-Segment Elevation Myocardial Infarction and Multivessel Disease: A Network Meta-Analysis
JAMA Cardiology
Cost-Effectiveness of a Polypill for Cardiovascular Disease Prevention in an Underserved Population
Journal of Clinical Endocrinology & Metabolism
Personalized Medicine in Acromegaly: The ACROFAST Study
Diabetes care
Diabetes Overtreatment and Hypoglycemia in Older Patients With Type 2 Diabetes on Insulin Therapy: Insights From the HYPOAGE Cohort Study
Chest
Neutrophil-Mediated Inflammatory Plasminogen Degradation, Rather Than High Plasminogen-Activator Inhibitor-1, May Underly Failures and Inefficiencies of Intrapleural Fibrinolysis
The American Journal of Respiratory and Critical Care Medicine
Lung Transcriptomics Link Emphysema to Barrier Dysfunction and Macrophage Subpopulations
Clinical Journal of American Society of Nephrology
Fracture in Association with Anticoagulant Therapy in Patients with CKD and Atrial Fibrillation
Albuminuria and Rapid Kidney Function Decline as Selection Criteria for Kidney Clinical Trials in Type 1 Diabetes Mellitus
Kidney International reports
Muscle Mass, Muscle Strength, and Health-Related Quality of Life in Kidney Transplant Recipients