Hi, This Week in Medicine, we will be discussing
First we will be discussing articles in New England Journal of Medicine
Alternative Complement Pathway Inhibition with Iptacopan in IgA Nephropathy
Atrasentan in Patients with IgA Nephropathy
Efficacy of Zenocutuzumab in NRG1 Fusion–Positive Cancer
Journal of American Medical Association
Simvastatin and Rifaximin in Decompensated Cirrhosis
A Randomized Clinical Trial
Age and Sex Differences in Efficacy of Treatments for Type 2 Diabetes
A Network Meta-Analysis
Annals of Internal Medicine
Effectiveness and Cost-Effectiveness of Expanded Targeted Testing and Treatment of Latent Tuberculosis Infection Among the Medicare Population in 2022
British Medical Journal
Frozen versus fresh embryo transfer in women with low prognosis for IVF treatment
Lancet
Traumatic injury mortality in the Gaza Strip from Oct 7, 2023, to June 30, 2024: a capture–recapture analysis
Journal of Clinical Oncology
OPAR: A Randomized Trial of Partial Breast Irradiation in Five Fractions Once Daily for Early Breast Cancer
Hepatology
ACMSD inhibition corrects fibrosis, inflammation, and DNA damage in MASLD/MASH
Gastroenterology
Obesity-Facilitated Colon Cancer Progression Is Mediated by Increased Diacylglycerol O-Acyltransferases 1 and 2 Levels
Clinical Gastroenterology
Satisfaction With and Adherence to Off-Label Corticosteroids in Adolescents and Adults With Eosinophilic Esophagitis: Results of a Web-Based Survey in the United States
Clinical Infectious Diseases
Antibiotic Prescribing for Respiratory Tract Infections in Urgent Care: A Comparison of In-Person and Virtual Settings
Rheumatology
Use of 18F-fluorodeoxyglucose Positron Emission Tomography to Monitor Disease Activity in Patients With Giant Cell Arteritis on Tocilizumab
Journal of Clinical Rheumatology
Nationwide Analysis of Variables Associated With Sarcoid Inpatient Mortality
Circulation
Large-Bore Mechanical Thrombectomy Versus Catheter-Directed Thrombolysis in the Management of Intermediate-Risk Pulmonary Embolism: Primary Results of the PEERLESS Randomized Controlled Trial
Journals of the American College of Cardiology
Secondary Prevention Medications in 17 Countries Grouped by Income Level (PURE): A Prospective Cohort Study
JAMA Cardiology
Microaxial Flow Pump Hemodynamic and Metabolic Effects in Infarct-Related Cardiogenic ShockA Substudy of the DanGer Shock Randomized Clinical Trial
Insulin Sensitivity and Insulin Secretion in Adults With Friedreich's Ataxia: The Role of Skeletal Muscle
Diabetes care
Large Language Model GPT-4 Compared to Endocrinologist Responses on Initial Choice of Glucose-Lowering Medication Under Conditions of Clinical Uncertainty
Neurology
Effect of IV Thrombolysis With Alteplase in Patients With Vessel Occlusion in the WAKE-UP Trial
Chest
A 1-Year Weight Management Program for Difficult-to-Treat Asthma With Obesity
A Randomized Controlled Study
The American Journal of Respiratory and Critical Care Medicine
Type 1 Immune Responses Related to Viral Infection Influence Corticosteroid Response in Asthma
Clinical Journal of American Society of Nephrology
Medication Burden and Adverse Cardiovascular Events and Death in Patients Treated with Maintenance Hemodialysis: A Nationwide Cohort Study
Kidney International reports
Implementation of a Kidney Genetic Service Into the Diagnostic Pathway for Patients With Chronic Kidney Disease in Canada
clinical utility, strategies to reduce the time from CKD diagnosis to genetics assessment are needed.
