Hi, This Week in Medicine, we will be discussing
New England Journal of Medicine
Twice-Yearly Lenacapavir for HIV Prevention in Men and Gender-Diverse Persons
Left Atrial Appendage Closure after Ablation for Atrial Fibrillation
Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours
The Genetic Architecture of Congenital Diarrhea and Enteropathy
Journal of American Medical Association
Cardiac Arrest During Long-Distance Running Races
Annals of Internal Medicine
The Effect of 4:3 Intermittent Fasting on Weight Loss at 12 Months: A Randomized Clinical Trial
British Medical Journal
Effects of intensive blood pressure treatment on orthostatic hypertension
Lancet
Pharmacokinetics and safety of once-yearly lenacapavir: a phase 1, open-label study
Journal of Clinical Oncology
Efficacy and Safety of Denileukin Diftitox-Cxdl, an Improved Purity Formulation of Denileukin Diftitox, in Patients With Relapsed or Refractory Cutaneous T-Cell Lymphoma
journal of Hepatology
Association of metabolic signatures of air pollution with MASLD: Observational and Mendelian randomization study
Gastroenterology
Glepaglutide, a Long-Acting Glucagon-like Peptide-2 Analogue, Reduces Parenteral Support in Patients With Short Bowel Syndrome: A Phase 3 Randomized Controlled Trial
Clinical Gastroenterology
Preinjection With Ligation-Assisted Endoscopic Mucosal Resection for Barrett’s Dysplasia and Early Esophageal Adenocarcinoma: Characteristic Histological Features of the Depth of Resection
Clinical Infectious Diseases
Peer-Assisted Telemedicine for Hepatitis C in People Who Use Drugs: A Randomized Controlled Tria
Rheumatology
Osteoclastogenesis in Patients With Systemic Sclerosis With and Without Calcinosis Cutis
Journal of Clinical Rheumatology
Age-Related Differences Between Juvenile and Adult Autoimmune Inflammatory Myopathies
Circulation
Clinical Outcomes With Normothermic Pulsatile Organ Perfusion in Heart Transplantation: A Report From the OCS Heart Perfusion Registry
Journals of the American College of Cardiology
New Threshold for Defining Mild Aortic Stenosis Derived From Velocity-Encoded MRI in 60,000 Individuals
JAMA Cardiology
Intravascular Sympathetic Stimulation to Facilitate Catheter Ablation of Premature Ventricular Complexes
Journal of Clinical Endocrinology & Metabolism
MBX 2109, A Once-Weekly Parathyroid Hormone Replacement Therapy Prodrug
Diabetes care
Diabetes Risk After Treatment for Childhood and Young Adult Cancer
Neurology
Associations of Plasma Neurofilament Light Levels With Brain Microstructure and Macrostructure and Cognition in the Community-Based Rhineland Study
Chest
Implementation and Effectiveness of Guideline-Recommended Clinical Activities for Children With Asthma
The American Journal of Respiratory and Critical Care Medicine
Temporal Exploration of Chronic Obstructive Pulmonary Disease Phenotypes: Insights from the COPDGene and SPIROMICS Cohorts
Clinical Journal of American Society of Nephrology
Performance of Creatinine and Cystatin-Based Equations on Estimating Measured GFR in People with Hematological and Solid Cancers
Kidney International reports
Systematic Review of the Effects of Iron on Cardiovascular, Kidney, and Safety Outcomes in Patients With CKD