Hi, This Week in Medicine, we will be discussing
First we will be discussing articles in New England Journal of Medicine
Exagamglogene Autotemcel for Severe Sickle Cell Disease
Exagamglogene Autotemcel for Transfusion-Dependent β-Thalassemia
Trial of Thrombectomy for Stroke with a Large Infarct of Unrestricted Size
Journal of American Medical Association
Ponatinib vs Imatinib in Frontline Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia
Associations of Internal Medicine Residency Milestone Ratings and Certification Examination Scores With Patient Outcomes
Annals of Internal Medicine
The Safety of Outpatient Health Care: Review of Electronic Health Records
Diagnostic Strategy Using Color Doppler Ultrasound of Temporal Arteries in Patients With High Clinical Suspicion of Giant Cell Arteritis: A Prospective Cohort Study
Nature Medicine
Single-cell transcriptomic analyses reveal distinct immune cell contributions to epithelial barrier dysfunction in checkpoint inhibitor colitis
Lancet
Preventive percutaneous coronary intervention versus optimal medical therapy alone for the treatment of vulnerable atherosclerotic coronary plaques (PREVENT): a multicentre, open-label, randomised controlled trial
Journal of Clinical Oncology
Phase II Trial of nab-Sirolimus in Patients With Advanced Malignant Perivascular Epithelioid Cell Tumors (AMPECT): Long-Term Efficacy and Safety Update
journal of Hepatology
Clinical profiles and mortality rates are similar for metabolic dysfunction-associated steatotic liver disease and non-alcoholic fatty liver disease
Molecular force-induced liberation of transforming growth factor-beta remodels the spleen for ectopic liver regeneration
Clinical Gastroenterology
Type 1 Autoimmune Pancreatitis in Europe: Clinical Profile and Response to Treatment
Screening for Fibrosis Promotes Lifestyle Changes: A Prospective Cohort Study in 4796 Individuals
ENTERPRET: A Randomized Controlled Trial of Vedolizumab Dose Optimization in Patients With Ulcerative Colitis Who Have Early Nonresponse
Clinical Infectious Diseases
Impact of a Purified Microbiome Therapeutic on Abundance of Antimicrobial Resistance Genes in Patients With Recurrent Clostridioides difficile Infection
A Systematic Review of Predictor Composition, Outcomes, Risk of Bias, and Validation of COVID-19 Prognostic Scores
Compared Performance of the 2023 Duke–International Society for Cardiovascular Infectious Diseases, 2000 Modified Duke, and 2015 European Society of Cardiology Criteria for the Diagnosis of Infective Endocarditis in a French Multicenter Prospective Cohort
Journal of Clinical Rheumatology
Measurement of Neutrophil Extracellular Traps as a Biomarker for the Differential Diagnosis Between Antineutrophil Cytoplasmic Antibody–Positive Individuals With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis and Nonautoimmune Diseases
Prediction of Treatment Effect of SLE-ITP Patients Based on Cost-Sensitive Neural Network and Variational Autoencoder
Arthritis and Rheumatology
Anti-Inflammatory Effect of High-Density Lipoprotein Blunted by Delivery of Altered MicroRNA Cargo in Patients With Rheumatoid Arthritis
American College of Cardiology
LGE CMR and Sudden Death in Hypertrophic Cardiomyopathy
Journals of the American College of Cardiology
Sacubitril/Valsartan-Related Hypotension in Patients With Heart Failure and Preserved or Mildly Reduced Ejection Fraction
Journal of Clinical Endocrinology & Metabolism
Association Between a History of Breast Cancer and Decreased Thyroid Cancer-specific Mortality
Neurology:
Association of Coffee Consumption and Prediagnostic Caffeine Metabolites With Incident Parkinson Disease in a Population-Based Cohort
Chest
Symptoms and Impaired Quality of Life After COVID-19 Hospitalization: Effect of Therapeutic Heparin in Non-ICU Patients in the Accelerating COVID-19 Therapeutic Interventions and Vaccines 4 Acute Trial
Use and Outcomes of Peripheral Vasopressors in Early Sepsis-Induced Hypotension Across Michigan Hospitals
The American Journal of Respiratory and Critical Care Medicine
Zinpentraxin Alfa for Idiopathic Pulmonary Fibrosis: The Randomized Phase III STARSCAPE Trial
Clinical Journal of American Society of Nephrology
Associations of Angiopoietin 2 and Vascular Endothelial Growth Factor-A Concentrations with Clinical End Points
The Association of Intra-Abdominal Adhesions with Peritoneal Dialysis Catheter-Related Complications
Kidney International reports
Early Rituximab as an Add-On Therapy in Children With the Initial Episode of Nephrotic Syndrome
Aversion to a High Salt Taste is Disturbed in Patients With CKD