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Hi, This Week in Medicine, we will be discussing

New England Journal of Medicine

Aficamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy

 

Intensive Ambulance-Delivered Blood-Pressure Reduction in Hyperacute Stroke

 Journal of  American Medical Association

Aspirin vs Placebo as Adjuvant Therapy for Breast CancerThe Alliance A011502 Randomized Trial

 

Smoking Cessation After Initial Treatment Failure With Varenicline or Nicotine ReplacementA Randomized Clinical Trial

 Annals of Internal Medicine

 

Efficacy of Voluntary Medical Male Circumcision to Prevent HIV Infection Among Men Who Have Sex With Men

 

Benefits and Risks Associated With Statin Therapy for Primary Prevention in Old and Very Old Adults

  British Medical Journal

Tislelizumab plus chemotherapy versus placebo plus chemotherapy as first line treatment for advanced gastric or gastro-oesophageal junction adenocarcinoma

 

Epidural analgesia during labour and severe maternal morbidity

  Journal of Clinical Oncology

Impact of Helicobacter pylori Infection and Treatment on Colorectal Cancer in a Large, Nationwide Cohort

 journal of Hepatology

Primary hypocholesterolemia is associated with an increased risk of hepatic complications in the general population

 Clinical Gastroenterology

 

 Validated Clinical Score to Predict Gastroesophageal Reflux in Patients With Chronic Laryngeal Symptoms: COuGH RefluX

 

Hypercholesterolemia Is Associated With Dysregulation of Lipid Metabolism and Poor Prognosis in Primary Biliary Cholangitis

  Journal of Clinical Rheumatology 

Choroidal Thickness Is a Biomarker Associated With Response to Treatment in Ankylosing Spondylitis

  Arthritis and Rheumatology

Effect of Recent Antirheumatic Drug on Features of Rheumatoid Arthritis–Associated Lymphoproliferative Disorders

 Circulation

Comparison of Incidence and Prognostic Impact of Ischemic, Major Bleeding and Heart Failure Events in Patients With Chronic Coronary Syndrome: Insights From the CORONOR Registry

 

American College of Cardiology

 

Coronary Atherosclerotic Plaque Activity and Risk of MI

  Journal of Clinical Endocrinology & Metabolism

Insufficient Bone Mineralization to Sustain Mechanical Load of Weight in Obese Boys: A Cross-Sectional Study 

 Neurology:

Distribution of Silent Cerebral Infarcts in Adults With Sickle Cell Disease

  Chest

Tolerability Outcomes of American Thoracic Society/Infectious Diseases Society of America Guideline-Recommended Multidrug Antibiotic Treatment for Mycobacterium avium Complex Pulmonary Disease in US Medicare Beneficiaries With Bronchiectasis

 

Prophylactic Minocycline for Delirium in Critically Ill Patients

 Clinical Journal of American Society of Nephrology

Sotagliflozin and Kidney Outcomes, Kidney Function, and Albuminuria in Type 2 Diabetes and CKD: A Secondary Analysis of the SCORED Trial

 

 Kidney International reports

Pregnancy and Family Planning in Women With Kidney Disease