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Hi, This Week in Medicine, we will be discussing

 New England Journal of Medicine

Belantamab Mafodotin, Bortezomib, and Dexamethasone for Multiple Myeloma

 Belantamab Mafodotin, Pomalidomide, and Dexamethasone in Multiple Myeloma

 

Autoantibodies Targeting Nephrin in Podocytopathies

  Journal of  American Medical Association

Projected Changes in Statin and Antihypertensive Therapy Eligibility With the AHA PREVENT Cardiovascular Risk Equations

 

Addiction Consultation Services for Opioid Use Disorder Treatment Initiation and EngagementA Randomized Clinical Trial

 Annals of Internal Medicine

 

Fatal and Nonfatal Firearm Injury Rates by Race and Ethnicity in the United States, 2019 to 2020

  British Medical Journal

 

Intraosseous versus intravenous vascular access in upper extremity among adults with out-of-hospital cardiac arrest: cluster randomised clinical trial (VICTOR trial)

  Lancet

Safety and efficacy of subcutaneous iscalimab (CFZ533) in two distinct populations of patients with Sjögren's disease (TWINSS): week 24 results of a randomised, double-blind, placebo-controlled, phase 2b dose-ranging study

  Hepatology

Post-treatment LSM rather than change during treatment predicts decompensation in patients with cACLD after HCV cure

 Clinical Gastroenterology

 

Effects of Food Insecurity on Hepatic Steatosis and Fibrosis in People With HIV

 

Vedolizumab, Adalimumab, and Methotrexate Combination Therapy in Crohn’s Disease (EXPLORER)

 Clinical Infectious Diseases

Community-Acquired Staphylococcus aureus Bacteremia Among People Who Inject Drugs: A National Cohort Study in England, 2017–2020 

 

A Randomized, Double-Blind, Phase 3 Safety and Efficacy Study of Ridinilazole Versus Vancomycin for Treatment of Clostridioides difficile Infection: Clinical Outcomes With Microbiome and Metabolome Correlates of Response 

 Arthritis and Rheumatology

Intra-Articular Mineralization on Computerized Tomography of the Knee and Risk of Cartilage Damage: The Multicenter Osteoarthritis Study

  Journals of the American College of Cardiology

Apixaban vs Aspirin According to CHA2DS2-VASc Score in Subclinical Atrial Fibrillation: Insights From ARTESiA

 

Semaglutide and NYHA Functional Class in Obesity-Related Heart Failure With Preserved Ejection Fraction: The STEP-HFpEF Program

 Journal of Clinical Endocrinology & Metabolism

Comparison of the Efficacy of Ezetimibe Combination Therapy and High-Intensity Statin Monotherapy in Type 2 Diabetes

   Neurology

Mechanisms of Hypercoagulability Driving Stroke Risk in Obesity: A Mendelian Randomization Study

  Chest

The Efficacy and Safety of Inhaled Antibiotics for the Treatment of Bronchiectasis in Adults

 

Early Deep Sedation Practices Worsened During the Pandemic Among Adult Patients Without COVID-19

  The American Journal of Respiratory and Critical Care Medicine

High Airway Occlusion Pressure Is Associated with Dyspnea and Increased Mortality in Critically Ill Mechanically Ventilated Patients

 

Clinical Journal of American Society of Nephrology

Genomic Testing in Patients with Kidney Failure of an Unknown Cause: A National Australian Study

 

  Kidney International reports

Randomized Controlled Trial of Intradialytic Cognitive and Physical Training to Enhance Functional Capacity

 

Outcomes of Early Versus Delayed Anemia Treatment in Nondialysis-Dependent CKD

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P2Y12 Inhibitors Refill Gap Predicts Death in Medicare Beneficiaries on Chronic Dialysis

 

Spectrum of Kidney Biopsy Findings Associated With Methamphetamine Use