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Hi, This Week in Medicine, we will be discussing

New England Journal of Medicine

Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity

Inhaled Fluticasone Furoate for Outpatient Treatment of Covid-19

Trial of Solanezumab in Preclinical Alzheimer’s Disease

JAMA

Two-Year Outcomes After Minimally Invasive Surfactant Therapy in Preterm Infants

Follow-Up of the OPTIMIST-A Randomized Clinical Trial

Annals of Internal Medicine

Comparative Safety Analysis of Oral Antipsychotics for In-Hospital Adverse Clinical Events in Older Adults After Major Surgery

A Nationwide Cohort Study

 

 The Effect of Low-Dose Glucocorticoids Over Two Years on Weight and Blood Pressure in Rheumatoid Arthritis: Individual Patient Data From Five Randomized Trials

 Nature Medicine

Longitudinal genomic surveillance of carriage and transmission of Clostridioides difficile in an intensive care unit

 British Medical Journal

Sensitivity, specificity, and diagnostic accuracy of WHO 2013 criteria for diagnosis of gestational diabetes mellitus in low risk early pregnancies: international, prospective, multicentre cohort study

Preconception contraceptive use and miscarriage: prospective cohort study

Objectives To evaluate the association between preconception contraceptive use and miscarriage.

Lancet

Effect of primaquine dose on the risk of recurrence in patients with uncomplicated Plasmodium vivax: a systematic review and individual patient data meta-analysis

 Clinical Infectious Diseases

Antiretroviral Therapy Intensification for Neurocognitive Impairment in Human Immunodeficiency Virus 

Journal of infectious Diseases

Bacterial Vaginosis and Spontaneous Clearance of Chlamydia trachomatis in the Longitudinal Study of Vaginal Flora

Journal of Clinical Rheumatology 

Disease-Modifying Antirheumatic Drug Use and Its Effect on Long-term Opioid Use in Patients With Rheumatoid Arthritis

 Circulation

Early Ablation for Atrial Fibrillation After Admission for Heart Failure

 Effect of Semaglutide 2.4 mg Once Weekly on Function and Symptoms in Subjects With Obesity-Related Heart FailureWith Preserved Ejection Fraction - STEP-HFpEF

 American Journal of Respiratory and Critical Care Medicine

FEV1/FVC Severity Stages for Chronic Obstructive Pulmonary Disease

 Mortality in Patients with Obesity and Acute Respiratory Distress Syndrome Receiving Extracorporeal Membrane Oxygenation: The Multicenter ECMObesity Study

 

Journal of Clinical Endocrinology & Metabolism

Efficacy and Safety of Low-dose Spironolactone for Chronic Kidney Disease in Type 2 Diabetes

 

Chloride and Potassium Assessment Is a Helpful Tool for Differential Diagnosis of Thiazide-Associated Hyponatremia

 

American journal of hypertension

Intensive Blood Pressure Control and Cardiovascular Outcomes in Elderly Patients: A Secondary Analysis of SPRINT Study Based on a 60-Year Age Cutoff