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Matt Maiocco and Jennifer Lee Chan break down the 49ers’ second-half collapse in their 24-23 home loss to the Arizona Cardinals. They analyze how Christian McCaffrey’s injury absence has led to San Francisco’s red-zone issues and how concerning the 49ers’ 2-3 start to the season has been.

4:00 Has CMC's absence led to 49ers' red-zone struggles?

10:00 Did heat play a part in second-half collapse?

22:30 How short week could be blessing in disguise for 49ers

28:15 Brandon Aiyuk's big game was bright spot

33:00 Why 49ers haven't been able to shut door on opponents

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