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Why is it so hard to lose weight permanently? Are our bodies programmed to "fight back" when we try to change our weight?

References:

Is there evidence for a set point that regulates human body weight? - PMC

Metabolic and Behavioral Compensations in Response to Caloric Restriction: Implications for the Maintenance of Weight Loss | PLOS One

Why you won't lose weight with exercise alone | ScienceDaily

Long-term follow-up of behavioral treatment for obesity: patterns of weight regain among men and women

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