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Listen to summaries of the latest oncology-focused research published in this week’s issue of Oncotarget, Volume 12, Issue 20.
https://www.oncotarget.com/archive/v12/i20/

Priority Research Paper (Cover) - “Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase”
https://doi.org/10.18632/oncotarget.28081

Research Paper - “A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs”
https://doi.org/10.18632/oncotarget.28079

Research Paper - “Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients”
https://doi.org/10.18632/oncotarget.28082

Research Paper - “Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells” https://doi.org/10.18632/oncotarget.28075

Research Paper - “Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells” https://doi.org/10.18632/oncotarget.28072

Research Paper - “Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma”
https://doi.org/10.18632/oncotarget.28074

Research Paper - “Multipeptide stimulated PBMCs generate TEM/TCM for adoptive cell therapy in multiple myeloma” https://doi.org/10.18632/oncotarget.28067

Research Paper - “NEDD8-activating enzyme inhibition induces cell cycle arrest and anaphase catastrophe in malignant T-cells” https://doi.org/10.18632/oncotarget.28063

Research Paper - “Safety and initial efficacy of ablative radioembolization for the treatment of unresectable intrahepatic cholangiocarcinoma” https://doi.org/10.18632/oncotarget.28060

Review - “Switching Hedgehog inhibitors and other strategies to address resistance when treating advanced basal cell carcinoma” https://doi.org/10.18632/oncotarget.28080

Editorial - “Fibrocytes in primary myelofibrosis”
https://doi.org/10.18632/oncotarget.27971 (PDF Download)

Research Perspective - “Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers”
https://doi.org/10.18632/oncotarget.27983

Keywords - cytokine profiling, breast cancer, colorectal cancer, colon cancer, lung cancer, multiple myeloma (MM), cellular therapy, T-cell lymphoma, cholangiocarcinoma, basal cell carcinoma, myelofibrosis, gastrointestinal cancer, cancer, science, research, oncology

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