What does Jesus mean when He says one of you is going to betray me? Well, because we know how the story ends, we know that Judas gives up Jesus' location to the Pharisees and the Romans in exchange for money. In doing so he unwittingly starts in motion God’s plan for Jesus to be executed and die for all humankind, thus satisfying God’s judgement and restoring our relationship with Him. The disciples however didn’t have the hindsight that we now live in.