A discussion about Acute Myeloid Leukaemia, from diagnosing to devising a personalised treatment plan. We run through the challenges in the initial treatment of APML, namely differentiation syndrome and DIC, and delve briefly into functional neutropenia.
Many thanks to Dr Andrew Wilson for his valuable insights. Andrew is a consultant haematologist at UCLH with a special interest in laboratory haematology and cancer education. Clinically he works in the MPN service and is one of the attending consultants for the leukaemia team. The rest of the time, he works in the UCLH Specialist Integrated Haematological Malignancy Diagnostic Service (SIHMDS) which reviews nearly 3,000 bone marrow samples every year. He is finishing his MA in clinical education and is keen to find ways to develop inter-professional learning.
For more reading, take a look at the following articles.
AML:
https://www.nejm.org/doi/full/10.1056/NEJMra1406184
APML:
http://www.bloodjournal.org/content/111/5/2505?sso-checked=true
ALL:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520400/pdf/bcj201753a.pd
