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We are joined once again by Magdalena Dziadzio and John Dempster to discuss Secondary Immunodeficiencies. The immunology team supports patients following treatments such as Rituximab, CAR T-cells, Ibrutinib and autologous stem cell transplantation, due to the long term effects on their antibody production. John talks about how patients can self administer immunoglobulin therapy at home due to recent advances in subcutaneous routing. Our discussion also touches on XLA, HIV and Hepititis C.