Iron Ladies Unite: Dive into Iron Deficiency

Description

This month's FLOW delves into the 'Iron Ladies' research - they investigate iron deficiency's prevalence among women with bleeding disorders, the importance of routine screening, the challenges in setting standardized care practices, and the historical exclusion of women from clinical trials. Featuring Dr. Megnahn McCormick, a doctor passionate about treating iron deficiency.

Program Notes:

Episode Links:

Bloodstream Media: https://www.bloodstreammedia.com/
The Iron Ladies Study: The Iron Ladies: Prevalence and Risk Factors of Iron Deficiency in Females With Bleeding Disorders - McCormick - Haemophilia - Wiley Online Library
A study presenting the data available through the ATHN dataset on women and girls with bleeding disorders*

A Cross-Sectional Study of Women and Girls with Congenital Bleeding Disorders: The American Thrombosis and Hemostasis Network Cohort | Journal of Women's Health

*includes a discussion on how participation in the dataset is not complete and how work is being done to remedy this!

An article about the impact of Thalidomide on FDA regulation: How medical research changed after thalidomide
More in depth on Thalidomide: Clinical Trials in Pregnancy and the "Shadows of Thalidomide":Revisiting the Legacy of Frances Kelsey - PMC
Information about what is identified as a "normal" hemoglobin; and how women who are iron-replete hemoglobin values are similar to men: "These findings highlight sex-based inequities that lead to normalization of disease states and the critical need to update hematologic ranges truly reflective of iron repletion."

Sex, lies, and iron deficiency: a call to change ferritin reference ranges | Hematology, ASH Education Program | American Society of Hematology

2021 article, Iron Ladies: Variation in the Identification and Management of Iron Deficiency in Women with Bleeding Disorders: https://www.sciencedirect.com/science/article/pii/S0006497121030202

How's Your Flow?