Howie and Harlan are joined by cardiologist Ali Rahimi, the founder of ALYKA Health, which uses a personalized mobile app to help patients manage their heart health between doctor's visits. Harlan discusses new developments in GLP-1 obesity drugs, including untested microdose treatments; Howie reviews a landmark study investigating whether broad prostate cancer screening saves lives.
Show notes:
GLP-1 Drugs
"Microdosing aims to extend the lifespan of the GLP-1 compounding market"
NIH: Regulatory Framework for Compounded Preparations
Health & Veritas Episode 140: Lee Schwamm: Smarter Healthcare Systems With AI
"FDA takes on GLP-1 compounding boom with warnings about misleading marketing"
"Should You Microdose GLP-1 Drugs?"
"How microdosing GLP-1 drugs became a longevity 'craze'"
"Bidding war between Pfizer, Novo Nordisk for obesity startup Metsera escalates"
"Trump Negotiating Deal With Ozempic Maker to Sell Some Weight-Loss Drugs for $149"
"Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist for Obesity Treatment"
"How Ozempic's Maker Lost Its Shine After Creating a Wonder Drug"
Ali Rahimi
"Why High Blood Pressure Matters to Your Health"
Building a Better Delivery System: A New Engineering/Health Care Partnership
NIH: The 21st Century Cures Act
New Evidence on Prostate Cancer Screening and Breast Cancer Treatment
National Cancer Institute: Cancer Stat Facts: Prostate Cancer"
U.S. Preventive Services Task Force: Prostate Cancer: Screening"
"The pros and cons of PSA tests for prostate cancer for midlife and older men"
"Share on European Study of Prostate Cancer Screening — 23-Year Follow-up"
"Early Detection of Prostate Cancer — Time to Fish or Cut Bait"
"Ten-Year Survival after Postmastectomy Chest-Wall Irradiation in Breast Cancer"
"Omission of Chest-Wall Irradiation after Mastectomy for Breast Cancer"
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