In this episode of the Parkinson's Podcast, learn about gene therapy for Parkinson's, including common misunderstandings and ongoing research about it.
This episode contains some technical terms and abbreviations. For your convenience, here is a short list of definitions that might be helpful.
AADC – Aromatic L-Amino Acid Decarboxylase: An enzyme that helps make dopamine (not a rock and roll band)
AAV – Adeno-Associated Virus: A harmless virus used to deliver gene therapy
CDNF – Cerebral Dopamine Neurotrophic Factor: A protein that helps keep dopamine-producing cells healthy
DBS – Deep Brain Stimulation: A surgical treatment that uses electrical signals to help control symptoms
GAD – Glutamic Acid Decarboxylase: An enzyme that helps rebalance brain circuits.
GBA – A gene linked to Parkinson's risk
GCH1 – GTP Cyclohydrolase 1: An enzyme that supports dopamine production.
GDNF – Glial Cell Line-Derived Neurotrophic Factor: A protein that helps protect brain cells
LRRK2 – A gene linked to Parkinson's risk
PARK2 – A gene linked to Parkinson's risk
PET – Positron Emission Tomography: A brain scan that shows chemical activity
PINK1 – A gene linked to Parkinson's risk
SNCA – A gene linked to Parkinson's risk
More information about Gene Therapy for Parkinson's is available here:
Sign up for updates on webinars, events, and resources for the Parkinson's community: https://dpf.org/newsletter-signup
