The bloods of the firstborn, maaser, and Pesach are only sprinkled once on the altar. This is derived from the fact that the word "saviv"-"around" the altar - appears in the context of the burnt, sin, and guilt offerings. One cannot learn from those cases to others, as details that appear two or three times cannot be used to establish a paradigm for a different case.
Rabbi Tarfon taught that the firstborn can be eaten for two days and one night, as it is similar to the peace offering. Rabbi Yosi Hagelili, on his first day in the Beit Midrash in Yavne, raised several difficulties with this comparison and likened it to a guilt and sin offering, which are eaten only for a day and night. When Rabbi Tarfon could no longer respond to the questioning, he left, and Rabbi Akiva took his place and said that in Vayikra 18:18, where the firstborn is compared to the thigh and breast given to the kohen, this is a juxtaposition between the firstborn and the peace offering. Rabbi Yosi Hagellil responded that also the thigh and breast are given to the kohen in a thanksgiving offering which is eaten only for a day and night. Therefore, perhaps the comparison should be made to the thanksgiving offering instead. Rabbi Akiva was convinced by Rabbi Yosi that the comparison should be to the thanksgiving offering, but he found other words in the verse from which to derive an additional day. When Rabbi Yishmael heard about this, he engaged in a lengthy debate with Rabbi Akiva regarding his change of position—that the comparison is to the thanksgiving offering. Rabbi Yishmael argued that the law of the thigh and breast in the thanksgiving offering is derived by juxtaposition (heikesh), and the law about the firstborn is derived from the thigh and breast by juxtaposition, and one cannot derive a law from a juxtaposition on a juxtaposition. However, the Gemara explains that this juxtaposition is not typical: while the law of the thigh and breast is derived by juxtaposition, the time limitation is stated directly. The debate between Rabbi Akiva and Rabbi Yishmael centers on whether a law derived partially by juxtaposition and partially stated explicitly can serve as the basis for a juxtaposition to another law.
The Gemara raises two difficulties with Rabbi Yishmael's position—one regarding the number of times the kohen gadol must sprinkle the blood of the bull and goat in the Sanctuary (Heichal) on Yom Kippur, and one regarding the amount of flour required for the loaves of matza that accompany the thanksgiving offering. Each of these laws is derived by means of a juxtaposition on a juxtaposition, along with something explicitly stated or derived by a gezeira shava. Each difficulty is resolved.
The Mishna stated that the Pesach may be eaten only until midnight. This is the opinion of Rabbi Elazar ben Azaria, but Rabbi Akiva permits it until dawn. Each derives their opinion from a different verse.
