This first episode delves into the clinical aspects of the Cryopyrin-Associated Periodic Syndromes and includes some helpful tips for sorting out some of the autoinflammatory diseases in the spectrum.
- Intro :10
- Cryopyrin-Associated Periodic Syndromes (CAPS) :25
- Outline of Part 1 2:25
- What is CAPS? 3:12
- Case #1 – a 25-year-old female with urticaria after cold exposure 4:25
- Case #2 – a 55-year-old female with progressive deafness 5:45
- The index case of familial cold autoinflammatory syndrome 9:00
- The final disease in the spectrum 11:00
- A lot of names for the same disease 13:50
- Genetics prove these three diseases are in the same spectrum 14:22
- Over 100 mutations have been found to-date 16:31
- Let's talk about mosaicism 17:03
- Disease characteristics of CAPS 18:15
- Neutrophilic infiltrate in chronic urticaria vs. CAPS 20:00
- Schnitzler syndrome 20:45
- Sensorineural hearing loss 21:58
- Joint pain 24:10
- Complication: Amyloidosis 25:29
- These diseases were very debilitating 28:38
- Episode recap 29:46
- Part 2 sneak peek 30:38
- Come say hi at ACR! 30:51
We'd love to hear from you! Send your comments/questions to rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum
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