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Dr. Sandra Kaufman on the Cellular Drivers of Aging and Practical Longevity Basics
Host Mike Roth interviews Dr. Sandra Kaufman, a longevity medicine leader with backgrounds in cell biology and anesthesiology, about why humans age and how to slow the process. Kaufman explains aging as progressive cellular dysfunction with multiple causes she groups into “seven tenets of aging,” arguing there is no single magic bullet and that mindset, mobility, and addressing pain matter. She recommends starting with basics—fixing underlying medical issues, improving diet and exercise—then layering in tools like supplements, medications, and therapies (saunas, cold, light). She says aging accelerates starting around ages 30–35 as key hormones and pathways decline, but longevity efforts can still improve quality of life. Kaufman highlights NAD precursors (NMN/NR) for energy and DNA repair support, discusses cancer risk as DNA repair failure, and shares her “PANACEA” supplement stack: pterostilbene, astaxanthin, NAD precursor, bioavailable curcumin, and carnosine.
00:00 Meet Dr Kaufman
01:02 Why We Age
02:14 Mindset And Daily Habits
03:42 Where To Start
04:53 Aging Starts Earlier
05:50 NAD Supplement Basics
07:28 Alzheimers Break
09:07 Cancer And DNA Repair
10:35 Peptides Stem Cells Exosomes
13:18 Cost And Patient Results
14:07 Panacea Supplement Stack
16:20 Wrap Up And Next Episode
Villages Vitality Senior Life Unscripted is Produced & Directed by Mike Roth
A new episode will be released most Fridays at 9 AM
Direct all questions and comments to mike@rothvoice.com
If you know a someone who should appear on the show, please contact us at: mike@rothvoice.com
