Keywords
Lung research, Respiratory tract, Human lung explants, Organoids, Air-liquid interface cultures, Infections, Drug testing, Disease mechanisms, Virology
Summary
In this episode of the Young Immunologist Podcast ImmunoChat, host Pia Leipe interviews Dr. Saskia Hinse, a postdoc at the University clinic Münster at the Institute of molecular Virology, to discuss models of the respiratory tract. They explore the use of human lung explants, organoids, and air-liquid interface cultures in lung research, focusing on their applications in studying infections, drug testing, and understanding disease mechanisms. The conversation highlights the advantages and challenges of these models, emphasizing their role in complementing traditional in vitro and in vivo experiments.
Takeaways
Please find here links to publications using the models discussed today - Lung explants, Organoids and ALIs:
https://pubmed.ncbi.nlm.nih.gov/39248230/
https://pubmed.ncbi.nlm.nih.gov/36423831/
Contact details
The Podcast is hosted by Pia Madeleine Leipe -
www.linkedin.com/in/pia-madeleine-l-75b749207
The podcast is supported by the German Association of Immunology (DGfI) - Young Immunologists (YI)
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https://dgfi.org/young-immunologists/
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