As of 2019, 0. 9 to 2. 9% of men in the United States are on TRT. As of 2017, testosterone prescriptions had increased 500% since 1993. Approximately 25% of men who receive TRT are not tested prior to treatment. Approximately 30% of men who get on it have no indication. They either are asymptomatic or they do not meet the clinical level of biomarker recommended by the American Urological Association (under 300 nanograms per deciliter). Of those treated, about half don't have their levels checked after therapy starts, despite 70% of men who receive TRT reporting subjective increases in well being. We have an increase in the number of men who are getting on this treatment - let's talk about it.