In this episode of MedEd Thread, we talk with Dr. Brian Mandell, Editor-in-Chief of the Cleveland Clinic Journal of Medicine, who discusses the evolving role of medical journal editors in an era of rapid research, digital transformation, and emerging technologies like AI. Dr. Mandell shares insights on managing peer review, maintaining editorial integrity, addressing predatory journals, and supporting trainee authors, while reflecting on how the COVID-19 pandemic and the rise of open access have reshaped the publishing landscape.