Description

Whipple's Disease explained, including microbiology of T.Whipplei and Whipple's Disease pathology. We look at the symptoms of Whipple's Disease including Classic and Local forms, as well as Whipple's Disease diagnosis and treatment. 

PDFs Available here: https://rhesusmedicine.com/

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Timestamps:
0:00 What is Whipple’s Disease?
0:20 Whipple's Disease - Trophyerma Whipplei Microbiology
0:51 Whipple’s Disease Pathology
2:35 Whipple’s Disease Symptoms
5:45 Whipple’s Disease Diagnosis
7:13 Whipple’s Disease Treatment 

References

1. Dolmans, R.A.V., Boel, C.H., Lacle, M.M. & Kusters, J.G., 2017. Clinical manifestations, treatment, and diagnosis of Tropheryma whipplei infections. Clinical Microbiology Reviews, 30(2), pp.529-555. [online] Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC5355640/ PubMed+1
2. MSD Manuals, 2025. Whipple disease. [online] Available at: https://www.msdmanuals.com/professional/gastrointestinal-disorders/malabsorption-syndromes/whipple-disease NCBI
3. BMJ Best Practice, 2025. Aetiology – Whipple disease. [online] Available at: https://bestpractice.bmj.com/topics/en-gb/467/aetiology
4. Mount Sinai Health System, 2025. Supranuclear ophthalmoplegia. [online] Available at: https://www.mountsinai.org/health-library/diseases-conditions/supranuclear-ophthalmoplegia
5. Marth, T., Moos, V., Müller, C. et al., 2016. Tropheryma whipplei infection and Whipple's disease. The Lancet Infectious Diseases, 16(3):e13-22. [online] Available at: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(15)00537-X/abstract PubMed+1

Please remember this podcast and all content from Rhesus Medicine is meant for educational purposes only and should not be used as a guide to diagnose or to treat. Please consult a healthcare professional for medical advice.