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In this episode of Reset Recharge, Dr. Komal Patil-Sisodia explores a groundbreaking study that reveals how menopause hormone therapy (MHT) may actually reduce the risk of type 2 diabetes in perimenopausal women with prediabetes.

Dr. Komal unpacks the data from a major Diabetes and Metabolism study of over 6,500 women aged 46–60, showing that those who used hormone therapy were 30% less likely to develop diabetes. She explains the science behind how estrogen supports metabolic health — improving insulin sensitivity, lowering inflammation, reducing central fat gain, and supporting pancreatic function — and why timing, age, BMI, and ethnicity make all the difference.

You’ll learn:

Whether you’re navigating perimenopause, supporting patients, or simply curious about hormone health, this episode breaks down complex science into practical takeaways you can use.

💡 Key takeaway: Menopause hormone therapy isn’t just about symptom relief — it can be metabolic protection for the right woman, at the right time.

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Eastside Menopause & Metabolism

Time Stamps:

00:00 – 00:54 | Welcome & Episode Overview  
00:55 – 02:30 | The Study That Sparked the Conversation  
02:31 – 04:00 | Who Benefits Most from Hormone Therapy  
04:01 – 06:00 | How Estrogen Supports Metabolic Health  
06:01 – 07:45 | The Timing Hypothesis Explained  
07:46 – 09:15 | Type & Route of Hormone Therapy Matter  
09:16 – 10:45 | Balancing Benefits and Risks  
10:46 – 12:15 | The Takeaway: Personalized Menopause Care  
12:16 – 13:06 | Closing & Next Steps

References:

Shih YH, Yang CY, Wang SJ, Lung CC. Menopausal hormone therapy decreases the likelihood of diabetes development in peri‑menopausal individuals with prediabetes. Diabetes Metab. 2024 Jul;50(4):101546. doi: 10.1016/j.diabet.2024.101546. Epub 2024 Jun 5. PMID: 38843591.

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