There was a massive explosion on March 11, 1597, when a stockpile of gunpowder on the docks in Dublin ignited. The explosion devastated central Dublin, killing 126 people, and halting city growth for decades. The explosion was in midst of a clerk's mismanagement of workers that lead to a porter strike. The strike causing an unusual build up of gunpowder.
Irish Mythology - Mythical Cycle - Book of Invasions