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The liver performs vital functions including filtering toxins, producing proteins, storing energy, aiding digestion, and regulating cholesterol and hormones. Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) has become the most common chronic liver disease globally, affecting up to 38% of the population worldwide.
• The liver filters blood, breaks down alcohol and medications, produces proteins like albumin and clotting factors
• It stores energy as glycogen, vitamins, and minerals including iron
• The liver makes bile for digesting fats and helps regulate cholesterol and support immune function
• Common liver problems include fatty liver disease, alcohol use, viral infections, and medication toxicity
• MASLD (formerly non-alcoholic fatty liver disease) occurs when too much fat builds up in the liver
• MASH is a severe form of MASLD with inflammation and damage that can lead to fibrosis and cirrhosis
• Up to 38% of people worldwide have MASLD, with prevalence rising to 65% in those with type 2 diabetes
• 5-10% total body weight loss can help slow, stop or reverse liver injury from MASLD
• The FDA recently approved semaglutide (Wegovy) as the first specific medication for treating MASH
• Regular check-ups with blood tests can help detect liver problems before symptoms develop
Stay healthy, and if you're concerned about your liver health, speak with your healthcare provider about testing and treatment options.
Production and Content: Edward Delesky, MD & Nicole Aruffo, RN
Artwork: Olivia Pawlowski