In this episode of Your Checkup, we explore a new study from the Mayo Clinic examining whether menopause hormone therapy enhances weight loss outcomes in postmenopausal women taking tirzepatide. Menopause is a major metabolic turning point — with rising visceral fat, declining muscle mass, and increasing cardiovascular risk. Researchers found that women using hormone therapy while on tirzepatide lost significantly more weight — nearly 5% more total body weight — and experienced additional cardiometabolic improvements compared to women not using hormones. We break down what this means, why estrogen may play a synergistic role, what the study does not prove, and how to think about personalized obesity treatment during midlife.
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Production and Content: Edward Delesky, MD, DABOM & Nicole Aruffo, RN
Artwork Rebrand and Avatars:
Vantage Design Works (Vanessa Jones)
Website: https://www.vantagedesignworks.com/
Instagram: https://www.instagram.com/vantagedesignworks?igsh=aHRuOW93dmxuOG9m&utm_source=qr
Original Artwork Concept: Olivia Pawlowski
