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A single biopsy changed modern medicine—and revealed a fault line that still runs through healthcare today. We dive into the story of Henrietta Lacks, a young Black mother whose cervical tumor cells were taken without her knowledge in 1951 and became the first immortal human cell line, known as HeLa. Those cells powered the polio vaccine, advanced cancer research, informed gene mapping, and helped unlock IVF and HIV treatments. Yet the breakthroughs came with a moral debt: the Lacks family was left uninformed, uncompensated, and burdened with the weight of a legacy built without consent.

We recount Henrietta’s life and the moment her cells began dividing endlessly in a lab, then unpack how HeLa reshaped research by enabling standardized experiments across the world. From vaccine development to drug screening and space biology, HeLa’s impact reaches into clinics, classrooms, and our daily lives. Alongside that impact, we confront the systemic exploitation of Black patients that made such a discovery possible without permission, connecting Henrietta’s story to a wider history of medical racism and the roots of enduring mistrust in healthcare.

Together we face the hardest questions: Who owns a body once tissue leaves the patient? What counts as informed consent for biospecimens and genetic data? How should institutions and companies share benefits when entire industries grow from a person’s cells? We offer practical ideas for a more just future—dynamic consent, plain-language disclosures, community oversight, and real benefit sharing—so progress is not only measured by cures, but by dignity.

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