In this episode, 3L1T3 sits down with Dr. Anne Wagner, clinical psychologist and founder of Remedy, whose research pushes MDMA therapy beyond the individual — into the space between two people. We explore what happens when couples facing PTSD enter treatment together, why trauma rarely belongs to just one partner, and whether psychedelic medicine can transform relational patterns where traditional therapy fails.
We also examine the ethical and emotional risks of dyadic MDMA therapy: consent, power dynamics, memory, boundaries, and what happens when only one partner improves. Is this the future of trauma care — or a dangerous leap?
This conversation challenges the standard medical model, questions the limits of psychedelic therapy, and asks whether healing sometimes requires more than one nervous system.
🎧 Plus: updates from Psychedelic Science 2025, upcoming guests like Leonard Pickard and Reggie Watts, and why the future of therapy might come in pairs.
⏱️ Chapters:
00:00 – Intro & Conference Check-In
04:22 – Meet Dr. Anne Wagner
04:38 – Misunderstandings About MDMA Therapy
07:13 – Empathy and Connection on MDMA
09:05 – Pilot Study Results from MDMA + CBCT
14:08 – Unexpected Dyadic Challenges
16:31 – Why Couples Therapy vs Solo MDMA Work
20:09 – Shifting Toward CPT + MDMA
24:18 – Preview of Anne’s Panels at PS25
28:57 – Defining Integration for Couples
32:35 – Will Dyadic Integration Become Its Own Field?
34:52 – Power Dynamics, Communication & Conflict on MDMA
37:22 – MDMA, Neurodivergence, and CPTSD
40:38 – Future of MDMA in General Relationship Work
42:13 – Ethical Guardrails for Psychedelic Couples Therapy
44:50 – Risks of Untrained Psychedelic Facilitators
45:44 – Training Models for Dyadic Psychedelic Therapists
47:20 – Access, Regulation & Stigma Barriers
49:20 – Anne’s Origin Story: Psychedelics, Trauma & Relationships
51:23 – Most Unexpected Lesson from the Work
53:09 – How to Connect with Remedy Centre
54:02 – Final Thoughts & Psychedelic Science Plans
59:09 – Outro: PTSD Breakthroughs & Upcoming Guests
Music by Flintwick
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