Description:
Psilocybin therapy is generating excitement for its rapid antidepressant effects—but how can we know who it will actually help?
In this episode of Off Label: Data, Diagnostics, and the Future of Mental Health, Dr. Steve Rondeau explores the role of EEG in predicting individual responses to psilocybin therapy. We examine the emerging science behind neural oscillations, connectivity patterns, and biomarker profiles that could help clinicians identify ideal candidates and avoid unnecessary risks.
Going beyond “set and setting,” this conversation dives into the potential of personalized psychedelics, where brain data—not guesswork—guides treatment decisions. We also consider how EEG might be used to monitor therapeutic progress, predict relapse risk, and illuminate the neurobiological mechanisms of change during psychedelic experiences.
Whether you’re a clinician, researcher, or simply curious about the intersection of neuroscience and psychedelics, this episode offers a grounded, data-driven look at how technology might shape the next era of psychedelic-assisted care.
