We explain how to tolerate GLP-1 medications without miserable side effects while still reaching weight and metabolic goals. We share dosing strategy, real-world tips, and when to switch medications or choose other tools.
• GLP-1 approvals for diabetes and weight management
• Mechanism behind nausea, constipation and reflux
• Start-low, go-slow dosing with patient control
• Long-term benefits for heart, kidneys and liver
• Injection site swap from abdomen to thigh
• Hydration and electrolyte timing across injection days
• Breakfast first, smaller frequent portions, more protein
• Avoid greasy foods, excess sugar and reflux triggers
• Fiber targets, stool softeners and cautious senna use
• Movement to aid gut motility
• Considering a switch from semaglutide to tirzepatide
• Alternative therapies including bariatric surgery
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