If you’ve ever wondered, “Should I increase my GLP-1 dose?” you’re not alone and the right answer is rarely just “go up because you can.” I’m Dr. Lindsay Ogle, a board-certified family medicine and obesity medicine physician, and I’m sharing the same framework I use in clinic to make GLP-1 titration decisions that are safe, personalized, and sustainable.
We start with the most overlooked rule: time. Because injectable GLP-1 medications have a long half-life, I want a full four weeks at a dose before we judge it. Then we walk through the decision points that matter most: GI side effects (nausea, reflux, bloating, constipation or diarrhea), whether you’re getting real appetite control and reduced food noise, and whether you can still eat enough protein, fiber, and overall calories to protect your energy, muscle mass, and metabolism. If a dose makes you skip meals or feel uncomfortably full after a few bites, “stronger” is not better.
We also talk about how to measure progress without getting trapped by the scale: clothes fit, body composition, waist circumference, and for metabolic goals like type 2 diabetes or prediabetes, blood sugar trends like A1C or continuous glucose monitor data. Finally, we address diet mentality, the real-world impact of medication cost, and why obesity is a chronic disease that often requires long-term treatment and a supportive care team.
Subscribe, share this with someone who’s considering a dose change, and leave a review so more people can find reliable, evidence-based guidance on GLP-1 medications and metabolic health.
How to Manage GLP-1 Side Effects:
Nausea: https://youtu.be/07-QFm71YMo?si=ySEQtNdf1Pph9-L2
Constipation: https://youtu.be/rog26mYgg9g?si=ER3jharJZ8F6K4GJ
Reflux: https://youtu.be/cwJfaq6CA-o
Advocacy Groups:
https://www.obesityaction.org/
Find a board certified Obesity Physician:
https://obesitymedicine.org/about/find-a-provider/
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