Evidence-Based Medicine (EBM) has been shaping clinical decision-making for more than three decades. In this episode, Dr. Busti walks through Step 1 of the 5 A’s — Ask, focusing on how to craft clear, answerable clinical questions that drive better evidence searches and stronger patient care decisions.
You’ll learn the difference between background and foreground questions, explore the structure of PICO (Population, Intervention, Comparison, Outcome), and understand how extensions like PICOT and PICOTS add precision by incorporating time and setting. Using practical clinical examples—from asthma and hypertension to acute coronary syndromes—Dr. Busti demonstrates how well-formed questions save time, sharpen focus, and improve clinical reasoning.
This episode also highlights how matching the question type to the best study design—from randomized trials to systematic reviews—helps clinicians and trainees efficiently identify the “best available evidence.” Whether you’re a student, resident, or practicing clinician, this foundational EBM skill will transform how you approach research and clinical problem-solving.
Listen, learn, and start building your foundation for the next steps of EBM—Acquire, Appraise, Apply, and Assess.
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Disclaimer: This content is for educational purposes only and is not intended to provide medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have heard in this content.
