When Fran was diagnosed with metastatic non-small cell lung cancer with brain metastases, she was offered one option: palliative radiation and more chemotherapy. She said no. Not because she gave up — but because she wanted a plan built for her, not a one-size-fits-all protocol.
In this episode of Outsmart Cancer, Dr. Dino Prato, founder of Envita Medical Centers, shares how precision oncology and immune-centric care helped Fran achieve a complete response — without traditional chemotherapy. Lung cancer is one of the most immunogenic cancers, yet standard immunotherapy often fails long-term because it isn’t properly targeted.
Dr. Prato explains how deep multi-omics mapping — including DNA sequencing, RNA transcriptomics, and immune spatial biology — revealed the exact immune targets needed to design Fran’s treatment. Using genetically targeted fractionated chemotherapy, custom-built immunotherapy, and autologous NK and dendritic cell therapies matched to her DAMPS, the immune system was trained to recognize and eliminate cancer throughout the body — including across the blood–brain barrier.
Instead of exhausting the immune system with high-dose chemo or palliative radiation, this approach focused on immunogenic cell death, real-time liquid biopsy monitoring, metabolic support, and precision drug selection (on-label, off-label, repurposed, and phytotherapeutic). The result: tumor clearance, restored energy, and durable immune control.
🎯 What You’ll Learn in This Episode:
• Why lung cancer is highly responsive to immunotherapy — when targeted correctly
• Why PD-1 inhibitors often fail without immune spatial biology
• How DAMPS guide immune training and immunogenic cell death
• The role of NK cells and dendritic cells in clearing metastatic disease
• How microdosed, targeted chemo reaches the brain without severe toxicity
• Why DNA alone isn’t enough — and RNA + immune mapping change everything
• How liquid biopsies (CTCs, ctDNA, methylation) monitor remission early
• Why precision oncology replaces “step therapy” with a custom playbook
📍 Envita Medical Centers – Scottsdale, AZ
🌐 Learn more: www.envita.com
📞 Speak with a care coordinator: 866-830-4576
“Refusing chemo doesn’t mean refusing hope — it means choosing precision.”
Disclaimer
This podcast is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your licensed healthcare provider before making any medical decisions. Individual results will vary, and Envita Medical Centers does not guarantee outcomes. Some treatments discussed may not be FDA-approved or available in all locations. Testimonials are shared with patient consent and may not reflect typical results. Do not delay or disregard professional medical care based on the podcast's content. Certain treatments may be available only at Envita’s international clinic in Hermosillo, Mexico. No specific outcomes are promised or implied.
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Outcomes Disclaimer
The results referenced from Envita's Precision Cancer Care: 35-Fold Improvement in Response Rates are from a retrospective analysis of 199 late-stage cancer patients treated at Envita Medical Centers between 2021 and 2023, as published in the Journal of Cancer Therapy. These outcomes are not guaranteed and will vary based on individual factors such as cancer type, stage, genetics, immunity and prior treatments. Any comparisons to standard care or clinical trials are based on published data and internal analysis, not head-to-head studies. Individual results will vary.
You can read the full peer-reviewed study at:
