๐ New insights from Cell shine a light on an unexpected ally in the fight against cognitive decline. A natural experiment from Wales shows that the shingles (herpes zoster) vaccine doesn't just prevent viral reactivationโit may also reduce new mild cognitive impairment and lower dementia-related mortality over long-term follow-up.
๐ Using a strict birthday-based eligibility cutoff, the study provides causal evidenceโrare in population dementia researchโthat vaccination may slow disease across its entire course.
๐ง โจ As we rethink neuroinflammation, immunosenescence, and healthy aging, this work opens the door to exploring broader neuroprotective effects of adult vaccines.
๐ A reminder that sometimes the smallest public health interventions carry the biggest, most surprising benefits.