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🔬 Anemia & Folate: Key Insights

 

🩸 Anemia is primarily caused by iron deficiency in the U.S., especially in pregnancy (30% prevalence).

📊 NHANES data shows high iron deficiency in young females (up to 77.5% at ferritin <50 μg/L).

⚠️ Causes include heavy menstrual loss, increased pregnancy needs, and low dietary heme iron.

💊 Iron supplements (18 mg/day) help, but >45 mg/day may cause nausea & constipation.

👶 Maternal iron status affects infant birth weight, and delayed cord clamping improves newborn iron stores.

🌍 In low-income countries, anemia is also linked to malaria, parasites, and hemoglobinopathies.

🍞 Folic acid fortification since 1998 has reduced neural-tube defects, making folate deficiency rare in the U.S.